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Updated: Jul 21, 2025

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
07:49

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling

Published on: August 3, 2018

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西格玛-1受体激活对TGFβ2-诱导的TRABECULAR MATRIX变化在人体肌网状细胞中具有保护作用

Minh Ngoc Tran1,2,3, Timea Medveczki1,2, Balazs Besztercei4

  • 1MTA-SE Lendület "Momentum" Diabetes Research Group, Semmelweis University, 1083 Budapest, Hungary.

Life (Basel, Switzerland)
|July 29, 2023
PubMed
概括

像fluvoxamine这样的西格玛-1受体 (S1R) 激动剂可能会保护尾管网 (TM) 免受损伤. 这项研究发现S1R激动剂逆转了TM细胞中TGFβ2诱导的变化,可能维持正常的眼内压力 (IOP).

关键词:
西格玛-1受体是一个受体.在TGFβ2中.细胞骨重塑 细胞骨重塑细胞外矩阵是细胞外矩阵.这种药物是fluvoxamine.玻璃眼 glaucoma 玻璃眼 玻璃眼 玻璃眼 玻璃眼眼内压力 眼内压力流出通道阻力 阻力 阻力它们的扩散和扩散.状网状网状网状网状网状网状网.

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