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丸胚芽细胞瘤的器官保存手术:当前的前景
Esther García Rojo1,2, Gianluca Giannarini3, Borja García Gómez2,4
1Department of Urology, Hospital Universitario HM Sanchinarro, 28050 Madrid, Spain.
Medicina (Kaunas, Lithuania)
|July 29, 2023
概括
对于丸生殖细胞瘤而言,节能器官手术提供了一个安全的替代方案,可以替代激进的整形切除术,在大多数患者中保留丸功能. 仔细的患者选择是成功结果的关键.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 手术瘤学手术瘤学
背景情况:
- 丸生殖细胞瘤需要平衡癌症控制和器官保存的治疗.
- 节能器官手术 (OSS) 是激进管切除的替代方案.
研究的目的:
- 评估OSS对丸生殖细胞瘤的瘤和功能结果.
- 讨论外科手术技术,并发症以及OSS的候选人选择.
主要方法:
- 在PubMed,Embase和Cochrane图书馆进行了全面的文献搜索.
- 包括报告手术技术,并发症和OSS的结果的研究.
- 分析了瘤控制,复发率,并发症率和功能结果.
主要成果:
- OSS显示了足够的瘤控制,复发率和并发症率较低.
- 在80-90%的患者中保持内分泌丸功能;父权在~50%中实现.
- 候选人选择标准包括正常的激素水平,双边瘤,单独的丸和瘤大小<50%的丸.
结论:
- OSS是丸生殖细胞瘤的安全有效选择,平衡癌症控制和功能维护.
- 需要进一步的大规模前性研究来验证OSS的有效性,并完善患者选择.
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