来自驼牛奶的细菌细菌PM5增强了的免疫力和废弃物 沙门氏菌感染
Ashraf Khalifa1,2, Hairul-Islam Mohamed Ibrahim1,3, Abdullah Sheikh4
1Biological Science Department, College of Science, King Faisal University, P.O. Box 400, Al-Ahsa 31982, Saudi Arabia.
Microorganisms
|July 29, 2023
概括
研究人员探索了驼奶益生菌作为家禽的抗生素替代品. 细菌细菌PM5显著减少了沙门氏菌感染,增强了免疫反应,改善了的肠道健康,为家禽生产提供了有前途的天然解决方案.
科学领域:
- 微生物学和免疫学
- 动物科学和家禽生产
- 食品科学与技术 食品科学与技术
背景情况:
- 超过五十年来,家禽业一直依赖抗生素,导致对抗生素替代品的兴趣增加.
- 益生菌为减少肠道疾病和提高牲畜生产率提供了一个潜在的解决方案.
- 驼牛奶是动物卫生应用新型益生菌菌株的潜在来源.
研究的目的:
- 从驼牛奶中分离和描述益生菌细菌.
- 评估隔离益生菌对家禽沙门氏菌感染的疗效.
- 评估益生菌对宿主免疫发育和的肠道健康的影响.
主要方法:
- 从驼牛奶样本中分离和选13种细菌菌株.
- 针对禽类病原体 (沙门氏菌,沙门氏菌,黄金葡萄球菌,大肠杆菌) 的抗菌活性测试.
- 使用模型进行体内研究,以评估Bacillus subtilis PM5对沙门氏菌感染,免疫反应和肠道参数的影响.
主要成果:
- 细菌细菌PM5表现出强大的抗菌活性和显著的非极性表面特性.
- 口服B. subtilis PM5显著降低了沙门氏菌进入器官的透率和的便量.
- 益生菌补充剂调节了粘膜免疫反应,减少了炎症标志物 (IL1-β,CRP,IFN-γ),并增加了肠道中的黄油酸水平.
结论:
- 从驼牛奶中分离出来的细菌细菌PM5对家禽具有显著的益生菌潜力.
- 补充B. subtilis PM5可以改善肉生长性能和对肠道病原体的耐药性.
- 这种益生菌为商业家禽料中的抗生素提供了可行的天然替代品,解决了消费者需求和生产挑战.
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