Mycobacterium marinum:一个基于病例的诊断和管理叙述审查
Giorgos Tsiolakkis1, Angelos Liontos2, Sempastian Filippas-Ntekouan2
1Department of Internal Medicine, Nicosia General Hospital, Nicosia 2029, Cyprus.
Microorganisms
|July 29, 2023
概括
非结核性菌根菌导致越来越频繁的皮肤感染. 这一案例突出了Mycobacterium marinum的诊断挑战,强调及时识别和治疗慢性病变.
科学领域:
- 皮肤病学 皮肤病学
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 非结核菌 (NTM) 越来越多地与皮肤和软组织感染有关.
- 来自NTM的慢性皮肤病变带来了诊断和临床挑战.
- 抗瘤坏死因子-α (抗TNF-a) 治疗可以加剧NTM感染.
研究的目的:
- 为了呈现一种Mycobacterium marinum感染病例.
- 审查M. marinum感染的流行病学,临床特征,诊断和管理.
- 为了强调与NTM皮肤感染相关的诊断复杂性.
主要方法:
- 一个66岁的男性患有状结节的案例介绍.
- 病变液的酸性污点. 病变液的酸性污点.
- 下一代测序 (NGS) 用于初始识别.
- 菌根菌培养以确定确诊 (8周).
- 关于M. marinum. 的文献评论.
主要成果:
- 患者在手和前臂上呈现疼痛结节,在抗TNF-a治疗后恶化.
- 酸速染色对菌根菌呈阳性.
- NGS确定了M. marinum,在8周的潜伏期后通过培养得到证实.
- 在诊断后,患者的病情得到了管理.
结论:
- 菌根菌感染需要专门的诊断方法.
- 早期和准确的诊断对于有效管理NTM皮肤感染至关重要.
- 临床医生必须意识到NTM,特别是M. marinum,在慢性皮肤病变中,特别是在免疫功能低下的患者或接受免疫调节疗法的患者中.
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