乳化剂甲酸盐-桑坦复合物对乳液的影响:稳定性和消化特性
Huan Huang1,2, Yan Tian1,2, Xinpeng Bai1,2,3
1School of Food Science and Engineering, Hainan University, No. 58 Renmin Avenue, Haikou 570228, China.
Molecules (Basel, Switzerland)
|July 29, 2023
概括
层层的吸附产生了优质的处女子油 (VCO) 纳米乳液. 这些蛋白质多糖稳定乳液表现出增强的稳定性和可消化性,使它们非常适合工业应用.
科学领域:
- 食品科学与技术 食品科学与技术
- 合体和表面化学
背景情况:
- 处女子油 (VCO) 纳米乳液是有前途的输送系统.
- 用蛋白质多糖化合物复合物稳定VCO纳米乳液是一个感兴趣的领域.
- 了解乳化剂排列对乳液特性的影响至关重要.
研究的目的:
- 为了比较VCO纳米乳液的稳定性和消化特性,这些纳米乳液通过不同的蛋白质-多糖化合物安排稳定.
- 为了评估酸盐 (SC) 和香甘 (XG) 的共吸附与层吸附对乳液性能的影响.
- 确定创建坚固和可消化的VCO纳米乳液的最佳方法.
主要方法:
- 使用超声波与SC和XG进行VCO纳米乳液的制备.
- 通过共同吸附 (SC/XG-VCO) 和层吸附 (SC-VCO-XG) 形成乳液.
- 在不同的pH值,离子强度,热量,冷解周期和储存条件下评估乳液稳定性;滴滴大小和泽塔电位测量;氧化稳定性和可消化性分析.
主要成果:
- 与SC/XG-VCO乳液 (共吸附) 相比,SC-VCO-XG乳液 (层吸附) 显示出更高的环境,氧化和储存稳定性.
- 层吸附还导致VCO纳米乳液的可消化性得到改善.
- 滴滴大小和泽塔潜力表明,层吸附乳液的物理稳定性得到了增强.
结论:
- 形成蛋白质多糖稳定乳液的方法显著影响其稳定性和可消化性.
- 通过层吸附 (SC-VCO-XG) 构建的乳液载体由于其增强的特性,更适合工业生产和开发.
- 这项研究为优化食品和营养药物应用的纳米乳液配方提供了宝贵的见解.
相关概念视频
Factors Influencing Drug Absorption: Pharmaceutical Parameters
154
Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
154
Colloids
17.6K
Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles that are visible to the naked eye or can be seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. On the other hand, a solution is a homogeneous mixture in which no settling occurs and in which the dissolved...
17.6K
Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry
230
Orally administered drugs primarily enter the systemic circulation via passive diffusion through the intestinal membranes. The drug's absorption is influenced by drug stability in the gastrointestinal GI tract, membrane permeability, the surface area available for absorption, luminal drug concentration, and residence time in the lumen. Drug permeability can be enhanced by adjusting the lipophilicity, polarity, or molecular size of the drug, promoting its passive transport across intestinal...
230
Complexation Equilibria: Factors Influencing Stability of Complexes
405
In complexation reactions, metal cations are the electron pair acceptors, and the ligands are the electron pair donors. The stability of the metal complexes depends primarily on the complexing ability of the central metal ion and the nature of the ligands. Generally, the complexing ability of the metal ion depends on the size and charge of the ion. As the metal ion size increases, the stability of the metal complexes decreases, provided that the valency of the metal ion and the ligands remain...
405


