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Updated: Jul 20, 2025

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设计和合成AMPK激活器和GDF15诱导器

Meijian Zhang1,2,3, Andrea Bagán4, Donna Martínez4

  • 1Department of Pharmacology, Toxicology and Therapeutic Chemistry, Institute of Biomedicine (IBUB), Faculty of Pharmacy and Food Sciences, University of Barcelona, Av. Joan XXIII, 27-31, 08028 Barcelona, Spain.

Molecules (Basel, Switzerland)
|July 29, 2023
PubMed
概括

研究人员开发了新的AMPK激活剂,以增加肥胖和2型糖尿病 (T2DM) 的生长分化因子15 (GDF15). 化合物21独特地提高了肝细胞中的GDF15蛋白水平,表现优于甲福林和BC1618.

关键词:
(1-二zylamino-3-phenoxy) -2-ol -2-ol -2-ol -1-dibenzylamino-3-phenoxy) -2-ol -2-ol -2-ol -1-dibenzylamino-3-phenoxy) -2-ol -2-ol -2-ol -1-dibenzylamino-3-phenoxy -1-dibenzylamino-3-phenoxy -1-dibenzylamino-3-phenoxy -2-ol -2-ol -1-dibenzylamino-3-phenoxy -2-ol -1-dibenzylamino-3-phenoxy -1-dibenzylamino-3-phenoxy) -2-ol -2-ol -2-ol -2-ol -1-dibenzylamino-3-phenoxy -1-dibenzylamino-3-phenoxy -1-dibenzylamino-3-phenoxy -2-ol -1-propan-2-ol -2-ol -2-ol -2-ol -2--2-这就是AMPKK.BC1618 BC1618 是一个在GDF15中,GDF15是GDF15中的一个.

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