炎症的严重程度与住院老年患者的食物摄入量有关 - 一个合并的数据分析
Maryam Pourhassan1, Tommy Cederholm2,3, Lorenzo M Donini4
1Department of Geriatric Medicine, Marien Hospital Herne, Ruhr-Universität Bochum, 44625 Herne, Germany.
炎症显著减少住院老年患者的食物摄入量,增加营养不良的风险. 较高的C-反应蛋白 (CRP) 水平是这种风险的一个关键指标.
科学领域:
- 老年医学 老年医学
- 临床营养学 临床营养学
- 炎症研究 炎症研究
背景情况:
- 炎症是老年患者营养不良的已知危险因素.
- 在这个人群中,炎症对食物摄入的确切影响需要进一步阐明.
- 全球营养不良领导倡议 (GLIM) 的标准强调营养不良是严重的健康问题.
研究的目的:
- 研究住院老年患者的炎症和减少食物摄入之间的关系.
- 用GLIM标准识别炎症作为营养不良的危险因素.
- 为了确定C-反应蛋白 (CRP) 水平对食物摄入量下降和营养不良的预测值.
主要方法:
- 来自五个欧洲国家的1650名住院老年患者 (≥65岁) 的合并数据集的分析.
- 使用迷你营养评估简单表格 (MNA-SF) 评估营养摄入量.
- 测量C反应蛋白 (CRP) 水平以量化炎症.
主要成果:
- 35%的患者的食物摄入量有所减少,28%的患者营养不良.
- 在不同程度的食物摄入量减少中,中位数CRP水平显著不同.
- 在三分之二的患者中,CRP水平≥3.0 mg/dL与食物摄入量减少有关,这表明营养不良的风险很高.
结论:
- 在住院老年患者中,炎症是低摄入食物和营养不良的最重要危险因素.
- 较高的CRP水平 (≥3.0 mg/dL) 强烈表明食物摄入量减少和营养不良的高风险.
- 早期识别和治疗炎症对于预防这一群体的营养不良至关重要.
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