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关于肠道衰竭相关肝病 (IFALD) 的当前见解:叙述性审查
Marija Zafirovska1,2, Aleksandar Zafirovski1,3,4, Nada Rotovnik Kozjek1,5
1Faculty of Medicine, University of Ljubljana, Vrazov trg 2, 1000 Ljubljana, Slovenia.
Nutrients
|July 29, 2023
概括
肠道衰竭相关的肝病 (IFALD) 影响肠道衰竭 (IF) 的患者. 本综述涵盖了IFALD的原因,预防,诊断和治疗,以改善患者的治疗结果.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 胃肠病学 胃肠病学
- 儿科和成人医学 儿童和成人医学
背景情况:
- 与肠道衰竭相关的肝病 (IFALD) 涵盖了一系列肝病,包括胆固醇病,胆道肝硬化,脂肪肝炎和胆囊病.
- 患病率差异很大,影响高达85%的新生儿,40-60%的儿科患者,15-40%的成年人患有肠衰竭 (IF).
- IFALD是由复杂的,多因素的原因引起的,包括肠外营养和患者特定的风险因素.
研究的目的:
- 审查目前关于IFALD病因学和病理生理学的知识.
- 检查关于IFALD的预防措施,诊断方法和治疗策略的最新证据.
- 为管理IFALD及其并发症提供全面的概述.
主要方法:
- 对IFALD.现有研究的文献综述.
- 综合有关风险因素和疾病机制的当前数据.
- 分析最近IFALD管理方面的进展.
主要成果:
- IFALD在患有IF的患者中呈现出一系列的肝脏疾病.
- 病因学是多因素的,涉及亲肠道营养和患者相关因素.
- 管理需要基于特定原因的多学科,个性化的方法.
结论:
- IFALD是肠道衰竭的显著并发症,具有不同的临床表现.
- 了解多因素病因对于有效管理至关重要.
- 为了预防和治疗IFALD及其并发症,一个量身定制的多学科战略至关重要.
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