输血传播疾病2023年,特别关注骨髓移植患者
Miklós Udvardy1, Árpád Illés1, Lajos Gergely1
1Division of Hematology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Pathogens (Basel, Switzerland)
|July 29, 2023
概括
输血医学面临着来自血液传播病原体的不断变化的威胁. 先进的查和无活化方法对于降低风险至关重要,特别是在接受输血的免疫受损患者中.
科学领域:
- 输血医学 输血医学
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 输血药物对于挽救生命至关重要,但会带来血液传播感染的风险.
- 新兴和重新出现的病原体对输血安全构成持续的挑战.
- 标准查和无活化方法可能无法检测所有输血传播的药物.
研究的目的:
- 突出证明和潜在的输血传播的病原体.
- 为了强调免疫功能低下的患者和骨髓移植接受者的风险.
- 强调需要先进的查和失活技术.
主要方法:
- 关于输血传播的病原体的文献综述.
- 分析新的和已知的传染病原体所带来的挑战.
- 专注于高风险患者群体,如免疫功能低下者和血友病患者.
主要成果:
- 已经确定了几种病原体是输血传播的,并且不断出现新的病原体.
- 免疫功能低下的患者和骨髓移植接受者面临更高的风险.
- 现有的查和无活化协议可能对新型或突变的病原体不够.
结论:
- 持续的警和更新的查/停活方法对于输血安全至关重要.
- 尽量减少输血相关的风险需要持续的研究和技术进步.
- 输血和血制品仍然至关重要,需要在益处和风险之间保持平衡.
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