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Updated: Jul 20, 2025

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在慢性炎症中PARPs和ADP-Ribosylation:关注巨细胞

Diego V Santinelli-Pestana1, Elena Aikawa1,2, Sasha A Singh1

  • 1Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Pathogens (Basel, Switzerland)
|July 29, 2023
PubMed
概括

异常的ADP-ribosylation由多多的ADP-ribose) 聚合酶 (PARP) /ADP-ribosyltransferase (ART) 酶影响慢性炎症. 本综述探讨了PARP/ART在巨细胞中的作用,强调了治疗开发的催化和非催化机制.

关键词:
在ADP-ribosylation过程中.类似于二菌毒素的ADP-ribosyl转移酶.这就是SARS-CoV-2病毒.酒精性肝病是一种肝病.树病毒 arboviruses 树病毒心血管疾病心血管疾病慢性感染 慢性感染突发性质炎症是什么意思主体病原体相互作用免疫力是一种免疫力.质谱测量质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量聚 (((ADP-ribose) 糖氨酸酶的使用情况.蛋白质组学 蛋白质组学

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