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Updated: Jul 20, 2025

A Novel Culture Model for Human Pluripotent Stem Cell Propagation on Gelatin in Placenta-conditioned Media
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布德索尼德类似物保持干细胞多能性,并延迟3D胃体发育

Filomena Amoroso1,2, Eduardo Ibello1,2, Federica Saracino1

  • 1Stem Cell Fate Laboratory, Institute of Genetics and Biophysics "A. Buzzati Traverso", Consiglio Nazionale delle Ricerche (CNR), 80131 Naples, Italy.

Pharmaceutics
|July 29, 2023
PubMed
概括

一种新的布德索尼德衍生物CHD-030498,在各种模型中有效地防止干细胞多能性损失. 这种小分子在调节细胞与细胞之间的相互作用和发育过程方面表现出比布迪索尼德更大的效力.

关键词:
3D 消化器 3D 消化器布德索尼德类似物毒性毒性毒性毒性毒性毒性毒性毒性毒性毒性毒多能性出口的出口.干细胞是干细胞的组成部分.

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The cells of the blastocyst inner cell mass only remain pluripotent for a short time. This state of pluripotency and self-renewal can be maintained in embryonic stem (ES) cell culture by adding specific chemicals or growth factors to ensure the cells can continue dividing and later differentiate into different cell types. In some cases, the cells are grown on a feeder layer of differentiated cells, which provides the growth factors and extracellular matrix components necessary for stem cell...
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