科隆U,从Plectranthus mutabilisCodd.中分离出来,由于线粒体抑制,导致P-糖蛋白活性降低

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Sofija Jovanović Stojanov1, Epole N Ntungwe2,3, Jelena Dinić1

  • 1Institute for Biological Research "Siniša Stanković"-National Institute of the Republic of Serbia, University of Belgrade, 11060 Belgrade, Serbia.

Pharmaceutics
|July 29, 2023
PubMed
概括

一种天然化合物Coleon U通过影响P-糖蛋白活性来对抗癌症的多药性耐药性. 它破坏了线粒体功能,导致癌细胞死亡,提供了一个新的治疗策略.

关键词:
科伦·乌·科伦这是一种P-glycoprotein蛋白.癌症多药耐药性 多药耐药性

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