从植物到伤口包裹和生物活性化合物的通过皮肤输送
Gabriela Olimpia Isopencu1, Cristina-Ileana Covaliu-Mierlă2, Iuliana-Mihaela Deleanu1
1Department of Chemical and Biochemical Engineering, University Politehnica of Bucharest, Polizu Str. 1-7, 011061 Bucharest, Romania.
Plants (Basel, Switzerland)
|July 29, 2023
概括
来自植物的天然化合物,包括牙和粘液,越来越多地用于先进的皮肤和透皮输送系统. 这些植物性材料为增强的生物医学应用提供生物相容性和成本效益.
科学领域:
- 生物医学工程 生物医学工程
- 药理学 药理学是指药理学的学科.
- 材料科学 材料科学 材料科学
背景情况:
- 通过皮肤输送设备和伤口包裹的不断进步,重点是提高有效性,生物相容性,生物降解性和成本效益.
- 在这些生物医学系统中,人们对利用自然化合物,特别是来自植物的化合物越来越感兴趣.
- 植物提供了大量和多样化的天然产品来源,传统的药用现在正在探索现代皮肤和皮肤应用.
研究的目的:
- 探索植物性化合物的潜力,包括来自和粘液的初级化合物,作为生物医学应用的具有成本效益和生物相容的组件.
- 为了研究植物衍生药用二次代谢物的药理学和毒理学影响.
- 介绍最近在隔离技术,药物输送系统和植物性天然产品评估程序方面的进展.
主要方法:
- 对皮肤和皮肤系统中植物衍生化合物的最新研究的综述和综合.
- 用于生物医学用途的植物性初级化合物 (牙,粘液) 的特性分析.
- 对其药理和毒理特征进行二次代谢物的研究.
主要成果:
- 植物性初级化合物,如牙和粘液,正在成为生物医学领域的有价值,具有成本效益,可生物降解和无毒的天然成分.
- 来自植物的二次代谢产物表现出广泛的药理作用,对医学有重大影响.
- 隔离,净化,药物输送系统和评估的创新技术正在加强这些天然化合物的应用.
结论:
- 植物性天然产品,从初级化合物到二次代谢物,对开发改进的透皮输送器件和伤口包裹有很大的前景.
- 植物材料的生物相容性,生物降解性和成本效益使其成为生物医学工程中的有吸引力的替代品.
- 对新型提取,输送和评估方法的持续研究将进一步释放这些自然资源在医学中的潜力.
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