织结构特征对人工血管性能的影响
Chenxi Liu1, Jieyu Dai1, Xueqin Wang1
1College of Textiles & Clothing, Qingdao University, Qingdao 266000, China.
Polymers
|July 29, 2023
概括
人造血管对于心血管疾病的治疗至关重要,当天然血管不足时. 针织,编织和织等织方法为开发这些重要的生物医学设备提供了独特的特性.
科学领域:
- 生物医学工程 生物医学工程
- 材料科学是一种材料科学.
- 织技术技术 织技术的使用
背景情况:
- 心血管疾病需要血管移植,但供体血管的局限性 (可用性,拒绝) 推动了对人工替代品的需求.
- 基于织品的管状织物为人工血管应用提供了有希望的合规性和灵活性.
- 生物相容的人造血管的开发对于解决供体短缺和改善患者治疗结果至关重要.
研究的目的:
- 审查和比较四种织品制造方法的人造血管:针织,编织,,和电.
- 分析不同织方法的结构特征对人造血管特性的影响.
- 为未来开发具有增强功能的人造血管提供指导.
主要方法:
- 在人造血管制造中对针织,编织,织和电技术的审查.
- 分析织方法影响的结构特征 (合规性,机械性能,孔径).
- 讨论改善生物相容性,抗菌性质和内皮质化的方法.
主要成果:
- 编织的血管具有卓越的机械性能和维度稳定性.
- 针织制造产生了出色的合规性,弹性和多孔性.
- 编织管可以轻松反弹和压缩;电旋提供了显著的生物效益.
- 结构参数的调整 (例如,编织角度,纤维细度) 可以优化孔隙性和合规性.
结论:
- 不同的织方法为人工血管设计提供了明显的优势,满足特定的功能要求.
- 定制结构参数和采用表面修饰技术可以提高人工血管的性能和生物相容性.
- 这一综述为选择和开发用于临床应用的先进人工血管提供了基础.
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