相关实验视频
Updated: Jul 20, 2025

08:31
Three-dimensional Optical-resolution Photoacoustic Microscopy
Published on: May 3, 2011
18.2K
自动化激光光纤合模块用于光学分辨率光声学显微镜
Seongyi Han1, Hyunjun Kye1, Chang-Seok Kim1
1Departments of Cogno-Mechatronics Engineering and Optics & Mechatronics Engineering, Pusan National University, Busan 46241, Republic of Korea.
Sensors (Basel, Switzerland)
|July 29, 2023
概括
本研究介绍了一种用于光声显微镜中的激光光纤合的自动化模块. 它通过优化激光传输,减少生物医学成像手动调整来提高图像质量和效率.
科学领域:
- 生物医学成像技术 生物医学成像技术
- 光学物理学的光学物理学
- 工程 工程师 工程师 工程师
背景情况:
- 光声学成像可视化了组织中的光学吸收.
- 光学分辨率的光声显微镜提供高空间分辨率.
- 高效的激光传输对于高质量的光声学图像至关重要.
研究的目的:
- 开发一个自动化的激光纤合模块,用于光学分辨率的光声学显微镜.
- 为了优化激光传递和最大限度地减少人工干预.
- 提高光声成像系统的效率和稳定性.
主要方法:
- 整合了安装在电机上的镜子支架,用于自动对齐.
- 实施比例导数 (PD) 控制以实现精确的激光传递.
- 使用叶子骨架幻象 (体外) 和人类手指 (体内) 的评估.
主要成果:
- 成功实现了高效和强大的激光传输.
- 从幻影和体内样本中展示高质量的光声学图像.
- 在合过程中大大减少了手动调节的需要.
结论:
- 自动化激光光纤合模块提高了光学分辨率光声显微镜的质量和效率.
- 这项创新简化了设置过程,使光声成像更容易获得.
- 该系统显示出在生物医学研究和临床诊断中具有更广泛应用的潜力.
相关概念视频
Confocal Fluorescence Microscopy
13.4K
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
13.4K
Imaging Biological Samples with Optical Microscopy
4.8K
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
4.8K
Super-resolution Fluorescence Microscopy
7.1K
Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
7.1K

