针对 Helicobacter pylori 根除的基于vonoprazan 的疗法的研究趋势:2015年至2023年的图书统计分析
Ren-Chun Du1, Yao-Bin Ouyang1,2, Nong-Hua Lu1
1Department of Gastroenterology, Digestive Disease Hospital, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Helicobacter
|July 29, 2023
概括
诺普拉桑在消除Helicobacter pylori感染方面表现出高效,特别是在四重治疗方案中. 研究趋势显示,日本是主要的贡献者,诺普拉桑在特定情况下的性能优于质子抑制剂.
科学领域:
- 对医学研究趋势的图书统计分析.
- 胃肠病学和传染病研究.
背景情况:
- 杆菌 (H. pylori) 感染仍然是一个重大的全球健康问题.
- 诺普拉桑是一种新兴的竞争性酸阻塞剂,显示出对H. pylori根除的前景.
- 了解研究趋势对于优化基于vonoprazan的治疗策略至关重要.
研究的目的:
- 进行对基于vonoprazan的治疗对H.pylori根除的研究的文献分析.
- 确定从2015年到2023年的关键研究趋势,热点和出版模式.
主要方法:
- 在 Web of Science 上使用术语"H. 皮洛里"和"沃诺普拉赞".
- 包括2015年至2023年间发表的65项研究.
- 研究的权重取决于被纳入评估影响的患者数量.
主要成果:
- 日本是最多产的国家,贡献了69.2%的出版物.
- 最常见的治疗方案是vonoprazan与阿莫西西林和澄素 (41.8%).
- 观察到高根除率:双重 (86.1%),三重 (89.3%) 和四重 (94.0%) 疗法 (每种方案).
- 诺普拉桑在经验和克拉里胺耐药H. pylori三重治疗中表现出优于质子抑制剂的优势.
结论:
- 诺普拉赞是广泛使用和有效的H. pylori根除.
- 需要进行进一步的研究,以确定不同地区的诺普拉桑治疗方案的最佳持续时间和剂量.
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