猫类运动性三症:使用不同的诊断方法对皮肤和皮肤外病变进行表征
Agna F Santos1, Maria I Azevedo2, Camila I Amaral1
1Pathology Sector and MULTILAB, Department of Clinic and Surgery, Veterinary School, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Veterinary pathology
|July 29, 2023
概括
猫的真菌感染 - - 球状三症通常会影响皮肤,并可能扩散到其他器官. 诊断涉及各种方法,其中组织病理学和细胞学是有效的,而免疫组织化学证实了低的真菌负载.
科学领域:
- 兽医真菌学 兽医真菌学
- 传染性疾病 传染性疾病
- 猫科病理学 猫科病理学
背景情况:
- 脊髓炎是一种由*Sporothrix*物种引起的真菌感染,主要影响皮肤和皮下组织.
- 它可以导致皮外表现,在受影响的动物中构成诊断挑战.
- 猫类性三病是一种严重的动物感染问题,特别是在巴西等地区.
研究的目的:
- 描述猫的皮肤和皮肤外运动性三病的临床和病理特征.
- 评估各种诊断技巧的疗效,以诊断猫类运动三症.
- 为了确定参与巴西贝洛霍里森特猫科动物感染的*Sporothrix*物种.
主要方法:
- 对102只疑似患有猫类胞三症的猫进行了尸检.
- 诊断技术包括宏观,细胞学,组织病理学和免疫组织化学 (IHC) 检查.
- 用于物种识别的真菌培养和聚合酶连锁反应 (PCR) 进行了测序.
主要成果:
- 使用至少一种诊断方法,在所有评估的猫 (n=102) 中证实了 *Sporothrix* 感染.
- 组织病理学 (68.6%) 和细胞学 (73%) 是有效的; IHC证实了低真菌负载 (93%) 的病例的诊断.
- 在74/102只猫中观察到皮外感染,包括鼻炎,淋巴腺炎,肺炎和脑膜炎. 鉴定出了巴西葡萄 (Sporothrix brasiliensis) 的存在.
结论:
- 所有被评估的猫都出现了 *Sporothrix* 感染,突出显示了组合死后方法的诊断实用性.
- 细胞学和细胞病理学对于诊断猫类胞菌有价值,对于低真菌负担病例来说,IHC是必不可少的.
- 皮外病变的高患病率表明显著的致病性,需要进一步调查疾病的慢性和真菌物种的毒性.
相关概念视频
Pulmonary Tuberculosis IV
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Toxoplasmosis
Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...


