双导管和双发光脑脊液分流系统,具有反流机制
Anup Patel1, David Qi1, Jacqueline Boyle1
1Department of Neurosurgery, University of Illinois College of Medicine at Peoria, Peoria, IL, USA.
概括
这项研究研究了使用双透导管用于在线去堵塞的腹腔导管的阻塞. 虽然回流显示阻塞有所减少,但结果在统计学上并不显著.
科学领域:
- 生物医学工程 生物医学工程
- 医疗器械技术 医疗器械技术
- 医疗器械中的流体动力学
背景情况:
- 导管堵塞是分流系统的重要并发症,特别是在水头治疗中.
- 新的体外模型对于测试导管设计和去阻塞策略至关重要.
- 之前的工作建立了一个模拟使用鸟类膜的导管封闭的台式装置.
研究的目的:
- 评估双光门导管介导逆流的整合,以在线解除阻塞的腹腔导管的阻塞.
- 为了评估通过一个分流系统组件的逆流在清除阻塞中的有效性.
主要方法:
- 一个双光通道连接连续连接到标准的近接分流通道.
- 使用微和双体电磁在预先确定的间隔内诱导逆流.
- 在实施回流之前和之后,测量了通道阻塞的流量和程度;还使用了流量可视化.
主要成果:
- 在基线阻塞率低于50%的情况下,回流在5分钟后在50%的试验中减少了阻塞,在延长回流后没有进一步的改善.
- 对于50%以上的基线阻塞,回流在5分钟后在20%的试验中减少了阻塞,在额外的回流后在40%的试验中改善了流量.
- 只有双体电磁系统中的磁板产生了足够的力量来实现脉动回流.
结论:
- 连接一个双光子导管连续连接一个近接导管显示了阻塞百分比的轻微变化与逆行流.
- 消除阻塞的有效性似乎与回流持续时间和初始导管阻塞百分比有关.
- 统计分析没有显示出近道导管封闭的显着减少,无论是回流间隔.
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