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瘤性肺癌与较低的整体生存率有关吗? 一个国家癌症数据库分析分析

Lauren M Poston¹, Aria Bassiri², Boxiang Jiang²

¹Case Western Reserve University School of Medicine, Cleveland, Ohio.

The Journal of surgical research

|July 29, 2023

概括

类肺癌是一种罕见的非小细胞肺癌 (NSCLC) 亚型,与其他NSCLC组织学相比,与明显较差的整体存活率有关. 需要进一步研究类肺癌的最佳分期.

科学领域:

在瘤学瘤学.
胸部外科手术胸部外科手术
癌症流行病学癌症流行病学

背景情况:

类肺癌是一种罕见的非小细胞肺癌 (NSCLC) 亚型.
现有的数据主要来自小型病例系列,限制了对其比较预后的理解.
与其他NSCLC组织学相比,类肺癌的整体存活率仍然在很大程度上是未知的.

研究的目的:

为了研究与其他NSCLC组织学相比,sarcomatoid肺癌患者的整体存活率.
为了确定与类肺癌相关的临床和人口特征.
为了确定影响类肺癌患者接受手术生存的因素.

主要方法:

使用国家癌症数据库 (2004-2018) 进行回顾性队列研究.
确定了非转移性NSCLC的成年患者,按组织学分类 (肉类瘤,腺癌,状细胞癌).
使用Kaplan-Meier和多变量Cox分析来评估整体存活率和相关因素.

主要成果:

类肺癌占肺癌病例的0.4% (5,223/1,259,109). 在肺癌病例中,类肺癌占0.4%.
瘤类患者更有可能是男性,西班牙裔,并发病率较少,疾病的晚期较高,但接受切除的频率更高.
类肺癌 (17.6个月) 与非类NSCLC (31.5个月) (P < 0.001) 的平均整体存活时间明显较低.

结论:

与其他NSCLC组织学相比,类肺癌与较低的整体存活率有关.
这些发现证实了较小的研究,并突出了这种罕见亚型的不良预后.
建议对类肺癌的最佳分期和治疗策略进行进一步的研究.

关键词:

没有小细胞肺癌的肺癌.肺部类癌症肺部类癌症外科手术的结果

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