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伪酸酶MK-STYX的DUSP域与G3BP1相互作用,以减少应力颗粒

Jonathan Smailys1, Fei Jiang1, Tatiana Prioleau1

  • 1Department of Biology, Integrated Science Center, William and Mary, Williamsburg, VA, 23185, USA.

Archives of biochemistry and biophysics
|July 29, 2023
PubMed
概括

密托基因激活蛋白激酶酸/氨酸/氨酸结合蛋白 (MK-STYX) 通过与G3BP1.1相互作用来减少压力颗粒. 它的DUSP域降低了G3BP1氨酸酸化,抑制了压力颗粒的形成.

关键词:
细胞分裂周期 25 酸酶同质性 2 细胞分裂周期具有双重特异性的域名.在 G3BP1 中使用.这是一个MK-STYX.蛋白质氨酸酸酶是一种蛋白质氨酸酸酶.伪酸酶是一种伪酸酶.压力颗粒是压力颗粒.

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