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作为通往心脏移植的桥梁,重复的门诊心脏病治疗
Javier de Juan Bagudá1, Fernando de Frutos2, Raquel López-Vilella3
1Servicio de Cardiología, Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain; Departamento de Medicina, Facultad de Ciencias Biomédicas y de la Salud, Universidad Europea de Madrid, Spain.
Revista espanola de cardiologia (English ed.)
|July 29, 2023
概括
重复的门诊levosimendan是等待心脏移植的患者的安全选择,可能减少心力衰竭住院. 这种治疗可以将患者连接到移植,而不会影响生存率.
科学领域:
- 心脏病学 心脏病学
- 药理学 药理学是指药理学的学科.
- 移植医学 移植医学
背景情况:
- 门诊心脏移植提供了一个潜在的桥梁到心脏移植 (HT).
- 有限的证据存在于重复的门诊levosimendan的安全性和有效性.
- 该LEVO-T注册表旨在评估其在HT候选物中的使用.
研究的目的:
- 描述接受 ambulatory levosimendan 作为通往 HT 的桥梁的患者简介.
- 分析levosimendan的处方模式和临床结果.
- 为了比较服用levosimendan的患者与未服用levosimendan的患者的结果.
主要方法:
- 在西班牙14个中心,从2015年至2020年,对1015名患者进行了选择性HT的回顾性审查.
- 接受和不接受levosimendan.com的患者之间的临床概况和结果的比较.
- 倾向性得分匹配分析用于控制混因素.
主要成果:
- 23.4%的患者接受了门诊治疗,这通常是由临床需要引发的.
- 莱沃西门丹的使用与更早的心力衰竭 (HF) 住院病例有关,但在HF住院病例或入院后1年生存率方面没有显著差异.
- 在HF入院后切换为levosimendan的患者,随后的HF入院减少了.
结论:
- 重复的门诊levosimendan对于等待HT的患者是一种常见的,安全的治疗方法.
- 这种方法可能有助于减少心力衰竭的住院治疗.
- 莱沃西蒙丹可以作为通往心脏移植的桥梁.
关键词:
心脏动剂是一种心脏动剂.这是心脏动力学.心脏衰竭是因为心脏衰竭.心脏移植心脏移植手术这是心脏衰竭 (cardiaca insuficiencia).西蒙丹丹 (Simendan) 是一个名字.西门达恩 (Simendán) 是一个这是一次心脏移植.更多相关视频
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