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近期在药理学应用和ptolide 肝毒性的进展

Dongxiao Cui1, Dingqiao Xu1, Shijun Yue1

  • 1Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine for TCM Compatibility, State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, Shaanxi University of Chinese Medicine, Xi'an, China.

Chemico-biological interactions
|July 29, 2023
PubMed
概括

特里普托利德在治疗癌症和自身免疫性疾病方面表现有前途,但由于肝脏毒性,其使用受到限制. 最近的研究探讨了这种毒性背后的机制,包括代谢,氧化和炎症途径.

关键词:
其他CYP450酶.肝毒性 肝毒性 肝毒性炎症 炎症是一种炎症.氧化应激是一种氧化应激.药理学应用 药理学应用三托利德是一种三托利德.

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