与交通相关的空气污染与自发的极度早产和其他不良周产期结果有关
Sara I Jones1, Jessica E Pruszynski1, Catherine Y Spong1
1Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX.
American journal of obstetrics and gynecology
|July 29, 2023
概括
怀孕期间接触二氧化与自发早产和新生儿并发症增加有关. 这种空气污染物也影响到预产婴儿,引发了对新生儿严重后果的担忧.
科学领域:
- 环境健康 环境健康
- 围产期流行病学 围产期流行病学
- 公共卫生 公共卫生
背景情况:
- 越来越多的人意识到空气污染与早产有关.
- 有限的数据存在于自发早产和严重的新生儿后果.
- 交通相关的空气污染是怀孕期间环境暴露的关键因素.
研究的目的:
- 检查交通相关的空气污染与周围产生的不良结果之间的联系.
- 调查与极端早产和新生儿重症监护室入院的联系.
- 评估对低出生体重,呼吸系统诊断,呼吸系统支持和败血症评估的影响.
主要方法:
- 在美国大都会地区对单独怀孕的回顾性队列研究.
- 根据EPA空气质量系统数据估计的二氧化 (NO2) 暴露.
- 经母体和人口因素调整后的物流回归.
主要成果:
- 与早产相关的NO2暴露较高 (aOR 1.94).
- 新生儿重症监护室入院和低出生体重的风险增加.
- 在自发早产和早期怀孕中,这种关联仍然存在.
结论:
- 与自发和极端早产相关的二氧化暴露增加.
- 新生儿不良结果,包括呼吸道问题和败血症评估,随NO2暴露而增加.
- 即使是满期的婴儿也显示出新生儿并发症的风险增加,随着NO2暴露的增加.
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