在失败的青光眼手术后,微导管辅助的周围垂切除术在儿童青光眼中失败
Lei Fang1, Yingting Zhu1, Shufen Lin1
1From the State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases (L.F., Y.Z., S.L., L.C., P.L., Y.Z., X.L.), Guangzhou, China.
American journal of ophthalmology
|July 29, 2023
概括
在以前的手术失败后,微导管辅助斜视切除术 (MAT) 有效地治疗儿童眼光病,包括初级先天性眼光病,青少年开角眼光病和二次儿童眼光病. 这种程序显著降低眼内压力和药物需求,没有严重的并发症.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 手术创新 在外科创新.
背景情况:
- 儿童绿内障,包括初级先天性绿内障 (PCG),青少年开角绿内障 (JOAG) 和二级儿童绿内障 (SCG),提出了重大挑战,特别是在最初的手术失败后.
- 有效的管理策略对于保护受影响儿童的视力至关重要.
研究的目的:
- 为了评估微导管辅助切眼术 (MAT) 的疗效和结果,作为治疗各种类型的儿童绿眼的治疗方法,此前的绿眼手术未成功.
- 评估MAT对眼内压力 (IOP) 的影响以及对青光眼药物的需求.
主要方法:
- 采用了回顾性干预案例系列设计.
- 分析了45只眼睛 (42名患者) 的数据,这些眼睛是患有童年青光眼的,在手术失败后接受了MAT手术.
- 术前和术后的内血压,青光眼药物的使用和成功率 (定义为内血压≤21 mm Hg) 进行了比较,至少12个月的随访.
主要成果:
- 与基线相比,MAT在所有研究的玻璃眼类型 (PCG,JOAG,SCG) 中显示出显著的IOP降低.
- 在所有患者组中,在MAT后观察到青光瘤药物数量显著下降 (P < .001).
- 取得的成功率很高:PCG的93.8%,JOAG的100%,SCG的88.9%,没有报告严重并发症.
结论:
- 微导管辅助斜视切除术 (MAT) 是一种有效的手术选择,用于治疗耐火性童年玻璃眼,包括PCG,JOAG和SCG.
- MAT提供了一种可行的解决方案,用于实现IOP控制,并减少有失败光瘤手术病史的患者的药物依赖.
- 该程序与有利的结果和良好的安全性相关.
相关概念视频
Angle Closure Glaucoma: Treatment
563
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
563
Open Angle Glaucoma: Treatment
480
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
480
Glaucoma: Overview
621
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
621


