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在患有神经性膀和肠道疾病的患者中,抗衰退前的尿清对膀功能的影响
Laura E Lorenger1, Ryan A Albright2, Douglas W Storm1
1Department of Urology, University of Iowa Hospitals & Clinics, Iowa City, IA, USA.
Journal of pediatric urology
|July 29, 2023
概括
在神经性肠道和膀 (NGB) 的儿童中,升级前的失禁清洗液 (ACE) 改善了便秘和压缩. 虽然一些患者的膀功能有所改善,但整体尿性没有显著改善.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 胃肠病学 胃肠病学
- 神经学 神经学
背景情况:
- 在儿童中,便秘往往与下泌尿道症状并存.
- 便秘管理对儿科神经性肠膀 (NGB) 膀功能的影响尚不清楚.
- 预发性失禁清洁剂 (ACE) 用于在NGB患者中治疗便秘.
研究的目的:
- 评估ACE通过Chait管对尿动力学研究 (UDS) 参数和NGB儿童尿的作用.
- 为了确定ACE是否能改善该群体的膀容量,服从性和稳定性.
主要方法:
- 对8名患有NGB的儿童进行了回顾性审查,这些儿童接受了以Chait管放置的乳房切割术.
- 纳入标准:UDS在手术前和后12个月内,干净间歇性导管注射 (CIC) 或抗胆固醇药物没有变化.
- 评估了UDS参数 (膀容量,符合性,稳定性),便秘,压缩,尿路感染 (UTI) 和尿.
主要成果:
- 在大多数患者中,便秘和压的显著改善 (p < 0.05) 被观察到.
- 25%的患者在CIC之间实现了尿失禁,另外2人表现出改善.
- 虽然在膀容量,服从性或稳定性方面注意到了一些个体改善,但在UDS参数或尿失禁方面没有显著的全组改善.
结论:
- 在NGB的儿童中,ACE可以改善便秘和压缩症,一些患者经历了膀功能和控制能力的增强.
- 对膀功能的积极影响似乎不那么明显,而不是在神经学上完整的儿童中出现便秘.
- 解决NGB患者的便秘是升级神经性膀医疗管理之前的合理初步步骤.
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