在人体内静脉植入器的下一个挑战
Joost Johannes Antonius Stultiens1, Richard F Lewis2, James O Phillips3
1Department of Otorhinolaryngology & Head and Neck Surgery, School for Mental Health and Neuroscience, Faculty of Health Medicine and Life Sciences, Maastricht University Medical Center, P. Debyelaan 25, Maastricht, 6202 AZ, The Netherlands. joost.stultiens@mumc.nl.
概括
一种新的前置神经假体旨在恢复双边前置病患者的平衡. 虽然有希望,但在优化刺激,手术和临床使用监管批准方面仍然存在挑战.
科学领域:
- 神经科学是一个神经科学.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 生物医学工程 生物医学工程
背景情况:
- 双侧静脉病变会给患者带来很大的负担.
- 目前的治疗方法对前庭功能障碍提供了有限的缓解.
- 静脉神经假体的开发灵感来自于耳植入技术.
研究的目的:
- 审查在2021年ARO中冬会议上提出的前体植入物开发方面的进展.
- 讨论向前置神经假体的挑战和未来方向,这些假体针对的是脉神经.
主要方法:
- 综述了研讨会的演讲和讨论.
- 专注于前置体植入物原型和耳-前置体植入物组合.
- 探索前置神经的电刺激.
主要成果:
- 在动物和人类研究中证明了前庭神经假体的可行性.
- 在开发前体植入物方面取得了实质性的进展.
- 一些研究小组正在积极研究原型设备.
结论:
- 关键的挑战包括优化刺激,外科手术和保护听力.
- 监管部门的批准和临床基础设施的发展至关重要.
- 克服这些障碍将加速前体植入物的临床应用.
相关概念视频
The Vestibular System
39.7K
The vestibular system is a set of inner ear structures that provide a sense of balance and spatial orientation. This system is comprised of structures within the labyrinth of the inner ear, including the cochlea and two otolith organs—the utricle and saccule. The labyrinth also contains three semicircular canals—superior, posterior, and horizontal—that are oriented on different planes.
39.7K
Equilibrium and Balance
4.8K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
4.8K


