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Updated: Jul 20, 2025

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
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双化酶OTUD7b通过稳定E3结合酶TRAF2来保护树突细胞免受TNF诱导的亡

Kunjan Harit1, Rituparna Bhattacharjee1, Kai Matuschewski2

  • 1Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, 30625, Hannover, Germany.

Cell death & disease
|July 29, 2023
PubMed
概括

卵巢瘤二基化酶7b (OTUD7b) 防止由瘤缩因子 (TNF) 诱导的树突细胞 (DC) 死亡,增强CD8+ T细胞反应. 这一发现为操纵免疫细胞存活提供了新的目标.

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