探索少数民族男性在治疗勃起功能障碍的恢复性治疗临床试验中的代表性:解决障碍并促进包容性
Braian R Ledesma1, Jamie Thomas1, Armin Ghomeshi2
1Desai Sethi Urology Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
International journal of impotence research
|July 29, 2023
概括
这项关于勃起功能障碍恢复性治疗的研究发现,通过有针对性的宣传,西班牙裔参与率更高. 战略改善了多样性,可能提高少数民族男性的健康结果.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 临床试验 临床试验
- 健康差异 在健康上的差异
背景情况:
- 勃起功能障碍 (ED) 影响着大量人群,代表性不足的少数群体经常面临临临床试验参与的障碍.
- 对于ED治疗的临床试验,例如富血小板血 (PRP),需要多样化的代表来确保发现的概括性.
- 加强临床研究多样性和包容性的战略对于解决健康差异至关重要.
研究的目的:
- 分析ED临床试验中代表性不足的少数民族男性的代表性.
- 确定促进多样性和纳入ED临床研究的有效策略.
- 将ED试验的PRP参与者人口统计数据与国家和当地人口数据进行比较.
主要方法:
- 对61名参与者的人口统计数据的回顾性描述性分析,用于治疗勃起功能障碍的富血小板血 (PRP for ED) 试验.
- 将试验的参与者患病率与国家和当地南佛罗里达源种群的比较.
- 评估实施的战略,包括双语员工和宣传材料,以评估它们对参与的影响.
主要成果:
- 针对ED的PRP试验招募了72.1%的西班牙裔参与者,明显高于全国患病率的39.9%.
- 种族组成显示了80.3%的白人,16.4%的黑人和3.4%的亚洲参与者,相比之下,全国数字为61.8%的白人,27.5%的黑人和1.5%的亚洲人.
- 通过文化敏感的策略加强了西班牙裔参与,包括双语员工和教育材料.
结论:
- 有针对性的,文化上适当的策略可以有效地提高少数民族男性在ED临床试验中的参与率.
- 成功招募西班牙裔男性表明,这些方法可以克服参与障碍.
- 提高ED研究的多样性对于解决健康差异和优化所有人群治疗结果至关重要.
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