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Updated: Jul 20, 2025

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微环境牛1诱导的免疫抑制促进黑色素瘤的生长

Marta Arumi-Planas1, Francisco Javier Rodriguez-Baena1, Francisco Cabello-Torres1

  • 1Instituto de Neurociencias (CSIC-UMH), Sant Joan d'Alacant, Spain.

Oncogene
|July 29, 2023
PubMed
概括

向Snail1在黑色素瘤微环境中,特别是在纤维细胞中,可以减少瘤生长和转移. 这种方法增强了抗瘤免疫力,为侵袭性皮肤癌提供了新的治疗策略.

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Preparation of Myeloid Derived Suppressor Cells MDSC from Naive and Pancreatic Tumor-bearing Mice using Flow Cytometry and Automated Magnetic Activated Cell Sorting AutoMACS14:15

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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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