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通过结合功能和结构信息,为驱动基因发现提供网络嵌入框架

Xin Chu1, Boxin Guan1, Lingyun Dai1

  • 1School of Computer Science, Qufu Normal University, Rizhao, 27826, China.

BMC genomics
|July 29, 2023
PubMed
概括

这项研究引入了一种新的网络嵌入框架,通过整合功能和结构基因信息来识别癌症驱动基因. 该方法增强了12种癌症的驱动基因发现,为癌症研究提供了新的视角.

关键词:
分类算法分类算法分类算法驾驶者基因 驾驶者基因基因相互作用网络的基因相互作用网络.突变数据 突变数据网络嵌入 网络嵌入.

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Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
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