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Updated: Jul 20, 2025

Bioengineering of Humanized Bone Marrow Microenvironments in Mouse and Their Visualization by Live Imaging
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皮肤介质保持和保护AML发起的干细胞

Lakshmi Sandhow1, Huan Cai1, Elory Leonard1

  • 1Department of Medicine Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden.

The Journal of experimental medicine
|July 30, 2023
PubMed
概括

在小鼠模型中,皮肤介质保护白血病干细胞免受化疗. 在这些中删除Lama4可以促进白血病干细胞的存活和化学抵抗,突出显示它们在急性髓性白血病 (AML) 复发中的作用.

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