血的噪音:血液流动器件对注册的影响
John D Lewis1,2, Vladimir S Fonov2, D Louis Collins2
1The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
Human brain mapping
|July 30, 2023
概括
大脑成像数据中的血流工件显著影响模板注册的准确性. 删除这些文物可以改善数据对齐,这对于神经成像研究中可靠的体积分析至关重要.
科学领域:
- 神经成像是一种神经成像.
- 医学图像分析 医学图像分析
- 脑部成像 脑部成像
背景情况:
- 血流器件在体积神经成像分析中是一个重大挑战.
- 这些工件可能会损害数据处理管道的准确性,特别是那些依赖于空间注册的管道.
- 自闭症脑成像数据交换 (ABIDE) 数据集提供了有价值的T1加权数据,具有突出的血液流动文物.
研究的目的:
- 评估血液流动工件对T1加权脑MRI数据到模板的注册的影响.
- 评估血液抑制技术在缓解这些人工物和提高登记质量的有效性.
主要方法:
- 利用了来自ABIDE数据集的T1加权数据,展示了血液流动的文物.
- 开发了一种启发式方法来识别和掩盖血液流动的文物.
- 通过用脑脊髓液强度替换人工物声来模拟血压.
- 登记原始和脱血数据到一个共同的T1加权模板.
- 使用相似度指标和测量非线性变形场的量化注册质量.
主要成果:
- 与原始数据相比,对模板注册的数据显示相似度值明显更高.
- 调整原始数据与已删除数据的注册位置所需的非线性变形是相当大的.
- 这些发现突出了血液流动器件对模板注册的有害影响.
结论:
- 血流器件对神经成像中的体积分析方法构成了严重的挑战.
- 脱血技术显著提高了T1加权数据注册到模板的准确性.
- 这些发现强调了解决血流器件对于可靠的神经成像数据处理和分析的重要性.
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