绘制区域大脑网络效率的演变,以及它与生命前28个月内认知能力的关联
Weixiong Jiang1, Zhen Zhou1, Guoshi Li1
1Department of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Developmental cognitive neuroscience
|July 30, 2023
概括
早期的大脑发育显示了复杂的区域效率变化. 特定的大脑区域的特定大脑区域
科学领域:
- 神经科学是一个神经科学.
- 发育神经科学的发展神经科学.
- 认知神经科学 认知神经科学
背景情况:
- 人类大脑在生命早期经历了显著的增长.
- 以前使用图形理论对早期大脑发育的研究主要集中在全脑拓属性上.
- 区域图形理论分析提供了对认知发展的独特见解的潜力.
研究的目的:
- 研究婴儿区域大脑效率的发育轨迹.
- 检查在早期发育过程中区域效率和认知能力的变化之间的关系.
- 探索这些关联中的与年龄相关的变化.
主要方法:
- 利用来自UNC/UMN婴儿结合体项目的大型纵向静止状态功能磁共振成像 (rsfMRI) 数据集.
- 使用图形理论指标分析区域,全球和本地效率.
- 区域效率的相关发育轨迹与早期学习的穆伦尺度 (长达28个月) 的认知分数.
主要成果:
- 揭示了区域,全球和地方效率的复杂,时空异质的发展模式.
- 在左尾状和双侧尾状之间发现了区域性全球效率和认知能力 (视觉接收,语言,早期学习复合) 之间的积极关联.
- 区域效率与认知之间的这些积极关联随着年龄的增长而减弱.
结论:
- 早期的大脑发育表现出网络效率的复杂区域差异.
- 在状区域的特定区域效率轨迹与幼儿时期的认知发展有关.
- 大脑网络的优化发生在整个大脑和区域层面,在生命的前28个月.
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