相关实验视频

Updated: Jul 20, 2025

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
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Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway

Published on: August 23, 2024

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达帕格利弗洛辛通过Sirtuin 1激活来预防氧化应激诱导的内皮功能障碍

Ying Zhou1, Shi Tai2, Ningjie Zhang3

  • 1Department of Blood Transfusion, The Second Xiangya Hospital of Central South University, Changsha 410011, China; Department of Cardiovascular Medicine, The Second Xiangya Hospital of Central South University, Changsha 410011, China.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|July 30, 2023
PubMed
概括

达帕格利弗洛辛是一种SGLT2抑制剂,通过减少氧化应激和促进血管松来保护内皮功能障碍. 它通过激活SIRT1来实现这一目标,从而增强内皮氧化合成酶 (eNOS) 的活性,并恢复NO的生物可用性.

关键词:
达帕格利弗洛辛 (Dapagliflozin) 是一种内皮细胞是内皮细胞.氧化应激是一种氧化应激.一个SIRT1系统.衰老,SGLT2 的时间.

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