在复发性复发性多发性硬化症患者中,疲劳与残疾和加速仪测量的日常体力活动的相关性
Marko Luostarinen1, Anne M Remes2, Pirjo Urpilainen1
1Institute of Biomedicine, Sports and Exercise Medicine, University of Eastern Finland, Kuopio, Finland.
Multiple sclerosis and related disorders
|July 30, 2023
概括
多发性硬化症 (MS) 患者的较低残疾和更好的身体状况与疲劳减少相关. 日常活动增加也预测疲劳减少,突出了管理这种常见的MS症状的关键因素.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 生物医学工程 生物医学工程
背景情况:
- 疲劳是多发性硬化症 (MS) 的普遍且具有挑战性的症状.
- 精确测量疲劳对MS患者日常生活的影响仍然很困难.
- 了解残疾,疲劳和体力活动之间的相互作用对于MS管理至关重要.
研究的目的:
- 调查复发性复发性多发性硬化症 (RRMS) 患者的残疾水平与他们的疲劳之间的关联.
- 探索加速仪测量身体活动与RRMS患者疲劳之间的关系.
- 确定身体状况和日常活动是否能预测MS患者的疲劳严重程度.
主要方法:
- 41名RRMS患者 (扩展残疾状况尺度[EDSS]0-5.5) 和20名对照患者完成了疲劳调查问卷 (MFIS,FSS).
- 使用EDSS,MS功能复合 (MSFC) 和六分钟步行测试来评估残疾.
- 参与者穿着加速度计七天来测量身体活动.
主要成果:
- 与对照组相比,在RRMS患者中观察到更高的疲劳水平,随着残疾的增加而增加.
- 在疲劳 (FSS/MFIS) 和残疾 (EDSS,MSFC) 之间发现了显著的相关性.
- 包括步骤在内的每日体力活动总量与疲劳严重程度 (FSS) 有负相关.
结论:
- 较低的残疾,改善的身体状况和更高的日常活动与MS的疲劳减少有关.
- 对身体活动的客观测量提供了对MS患者所经历的疲劳的洞察力.
- 这些发现表明了旨在减轻多发性硬化症疲劳的干预措施的潜在目标.
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