2022年全球乙型肝炎的流行率,护理级联和预防覆盖率:2022年乙型肝炎的全球流行率,护理级联和预防覆盖率:一个建模研究
The lancet. Gastroenterology & hepatology
|July 30, 2023
概括
全球乙型肝炎病毒 (HBV) 感染影响了25755万人,只有很少一部分人得到了诊断和治疗. 增加诊断和治疗对于实现2030年消除目标至关重要.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 世界卫生大会的目标是到2030年消除乙型肝炎病毒 (HBV) 感染作为公共卫生威胁.
- 现有的治疗和预防提供了一条可行的消除途径,即使没有治愈.
研究的目的:
- 估计全球,区域和国家HBV感染的流行率.
- 评估HBV的诊断,治疗和预防率.
- 在全球范围内预测未来的HBV疾病负担.
主要方法:
- 一个Delphi过程和文献评论为一个动态的马尔科夫模型 (PRoGReSs模型) 提供了信息.
- 为170个国家开发了模型,以估计2022年的HBV流行率.
- 在没有新的干预措施的情况下,预测了未来的发病率和死亡率.
主要成果:
- 全球HBV流行率在2022年为3.2% (25755万人),有3600万人被诊断出,6800万人接受治疗.
- 在5岁以下的儿童中,患病率为0.7% (5.6万名儿童).
- 疫苗接种覆盖率各不相同,有85%的人接种了三剂量系列,但只有46%的人接种了及时分娩剂量.
结论:
- 目前的战略不足以实现2030年HBV消除目标.
- 增加预防,诊断和治疗的努力是必不可少的.
- 为了实现公共卫生目标,需要紧急扩大干预措施.
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