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甲状腺瘤切除术后甲状腺功能低下症的危险因素
Julien Prévot1, Gaël Potard1, Philippe Thuillier2
1Department of Head, Neck surgery, University Hospital of Brest, 4, avenue Foch, 29200 Brest, France.
Annales d'endocrinologie
|July 30, 2023
概括
甲状腺切除术后的甲状腺功能低下是很常见的. 较高的手术前TSH和较小的剩余甲状腺体量预测其发展,需要对这些患者进行更密切的监测.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
背景情况:
- 甲状腺功能低下症是甲状腺节块的甲状腺切除术后经常出现的并发症.
- 确定预测因素对于患者管理至关重要.
研究的目的:
- 为了调查甲状腺功能减退术后甲状腺功能减退症的预后因素.
- 为了确定患有术后甲状腺功能低下症风险较高的患者.
主要方法:
- 对128名经过甲状腺切除术 (2016-2017) 的患者进行了回顾性队列研究.
- 排除患有手术前甲状腺功能低下或恶性瘤的患者.
- 主要终点:甲状腺功能低下的发展 (TSH≥2高于正常水平).
主要成果:
- 20%的患者在手术后出现甲状腺功能低下症.
- 确定了独立的预测因素:手术前的TSH>1.5mIU/L和剩余的甲状腺体体积<4.0mL/m2.
- 手术后的TSH水平与手术前值有显著的相关性.
结论:
- 手术前TSH>1.5mIU/L或甲状腺剩余体积小的患者需要加强临床和生物随访.
- 在甲状腺切除术后早期发现和治疗甲状腺功能低下症是必不可少的.
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