地中海饮食与刺激性肠综合征症状之间的关联
Ellie Y Chen1, Swapna Mahurkar-Joshi2, Cathy Liu2
1Vatche and Tamar Manoukian Division of Digestive Diseases, University of California, Los Angeles, Los Angeles, California.
概括
标准的地中海饮食 (MD) 并没有改善易怒肠综合征 (IBS) 的症状. 根据个体症状来个性化MD可能更有效地管理IBS及其肠道微生物群.
科学领域:
- 胃肠病学 胃肠病学
- 营养科学 营养科学
- 微生物组研究 微生物组研究
背景情况:
- 对地中海饮食 (MD) 的低坚持与更高的刺激性肠综合征 (IBS) 患病率有关.
- 对于MD坚持和特定的IBS症状之间的关联仍然不清楚.
研究的目的:
- 评估MD和IBS症状之间的联系.
- 为了确定与IBS症状严重程度相关的特定MD组件.
- 为了确定症状修饰的MD是否会影响肠道微生物群.
主要方法:
- 在106名IBS患者和108名对照组中评估了饮食摄入量和胃肠道症状.
- 采用标准化问卷来衡量地中海饮食的坚持.
- 在IBS受试者中,通过16SrRNA基因测序分析了肠道微生物组成.
主要成果:
- 标准的MD坚持得分与IBS症状严重程度没有相关性.
- 增加水果,蔬菜,糖和黄油的消费与更严重的IBS症状有关.
- 一种症状修饰的MD与减少有害肠道细菌 (Faecalitalea,Streptococcus,Intestinibacter) 和增加有益细菌 (Holdemanella) 相关联.
结论:
- 一个标准的MD并不是对所有IBS患者普遍有益的.
- 根据个体症状概况来个性化MD对于管理IBS至关重要.
- 以症状为导向的饮食修改显示出改变IBS肠道微生物组的潜力.
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