一种日常管理模式改善了患者对Helicobacter pylori感染治疗的遵从性:一项前性随机对照研究
Zhen Yang1,2, Wenjie Xiong1,2, Ruoyun Yang1,2
1Department of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, No.300 Guangzhou Road, Nanjing, 210029, Jiangsu Province, China.
Gut pathogens
|July 30, 2023
概括
日常 (DTD) 管理模式改善了Helicobacter pylori (H. pylori) 感染治疗的药物治疗和随访遵守. 然而,与标准门诊教育相比,它没有显著增加H. pylori根除率.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 健康管理健康管理
背景情况:
- 日常 (DTD) 管理模式通过目标设定来促进患者参与医疗保健.
- 这项研究将DTD模型的有效性与传统的门诊教育 (OE) 进行比较,用于治疗H. pylori感染.
研究的目的:
- 评估DTD模型在H. pylori感染管理中的有效性.
- 为了比较DTD和OE组之间的患者遵从性和治疗结果.
主要方法:
- 254名H. pylori阳性患者被随机分为DTD (127) 和OE (127) 组.
- 两组人都接受了为期14天的含有斯木的四倍疗法.
- DTD组自行监测每日药物服药的坚持和出席.
主要成果:
- DTD组表现出显著更高的药物遵从性 (P=.001 MITT,P=.031 PP) 和随访遵从性 (P<.001 MITT,P=.003 PP).
- 在DTD组 (P<.001) 中,尿素呼吸测试审查的时间也显著改善 (P<.001).
- 在H. pylori根除率 (95.8%与93.8%,P=.529 PP) 或不良事件 (25.4%与28.3%,P=.603) 中没有发现显著差异.
结论:
- DTD模型为H. pylori感染治疗提供了一种新的方法.
- 它有效地促进了患者习惯性服用药物的行为.
- 在没有医生干预的情况下,DTD模型提高了合规性,尽管根除率与标准护理相似.
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