RECREATE:在英国中风服务中进行多中心试点集群随机对照试验 (cRCT) 的研究协议,评估一种干预措施,以减少中风幸存者的久坐行为 (Get Set Go),并嵌入了过程和经济评估
Jennifer Airlie1, Louisa-Jane Burton2, Bethan Copsey3
1Academic Unit for Ageing and Stroke Research, Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK jennifer.airlie@bthft.nhs.uk.
BMJ open
|July 30, 2023
概括
这项试点试验调查了
科学领域:
- 脑卒中康复 脑卒中康复
- 公共卫生 公共卫生
- 临床试验 临床试验
背景情况:
- 久坐不动的行为与健康状况不佳有关,包括死亡率.
- 卒中幸存者表现出比健康成年人更高的久坐行为.
- "Get Set Go"干预措施旨在减少中风幸存者的久坐时间.
研究的目的:
- 试点为中风幸存者提供"Get Set Go"干预措施.
- 评估干预措施改善日常生活活动的潜力.
- 为未来的中风康复试验设计提供信息.
主要方法:
- 实用,多中心,外部试点集群随机对照试验.
- 15英国中风服务随机分为干预或常规护理.
- 招募了300-400名中风幸存者和护理人员; 24个月的随访.
主要成果:
- 干预对诺丁汉日常生活活动扩展范围的影响的初步估计.
- 计划进行探索性终点分析.
- 过程评估,以评估干预的真实性和可接受性.
结论:
- 试点试验将提供有关"Get Set Go"可行性和潜在有效性的数据.
- 这些发现将指导在中风康复中进行更大规模的最终试验的设计.
- 这项研究解决了减少中风后久坐行为的干预措施的需要.
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