心脏-关节血管指数和左心房逆向重塑,在为心房移除后进行
Issei Yoshimoto1, Hitoshi Ichiki1, Masaaki Miyata1
1Department of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University.
International heart journal
|July 30, 2023
概括
用心脚血管指数 (CAVI) 测量的下动脉硬与心房动 (AF) 除后成功的左心房逆转型 (LARR) 有关. 这一发现表明,CAVI可能预测AF患者的LARR结果.
科学领域:
- 心脏病学 心脏病学
- 血管生物学 血管生物学
- 电子生理学 电子生理学
背景情况:
- 动脉刚性有助于左心房 (LA) 重塑和心房动 (AF).
- 左心房逆转型 (LARR) 是AF切除后的一个关键结果.
- 心血管指数 (CAVI) 量化了动脉硬度.
研究的目的:
- 为了研究术前动脉硬 (CAVI) 和AF切除后的LARR之间的关联.
- 为了确定CAVI是否可以预测AF和LA扩大的患者在导管切除后成功的LA重塑.
主要方法:
- 分析了一组333名患有AF和LA扩大,接受AF切除的患者队列.
- 在手术前测量了CAVI.
- LARR被定义为6个月后的LA体积指数≥15%的下降.
主要成果:
- 与没有LARR的患者相比,获得LARR的患者手术前CAVI显著降低 (7.80 ± 1.22对比8.57 ± 1.09,P < 0.001).
- 手术前的CAVI与LARR独立相关 (OR,0.60;95%CI,0.46-0.78;P<0.001). 这两种情况均有相关性.
- 在LARR组中观察到更高的鼻节律维持率.
结论:
- 在患有AF和LA扩大的患者中,手术前CAVI是导管切除后LA逆重塑的独立预测因素.
- 降低动脉硬性可能有助于有利的LA改造AF移除后的AF.
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