运动重塑大脑:与认知改善相关的分子,细胞和结构变化
Marcus Augusto-Oliveira1, Gabriela P Arrifano2, Caio G Leal-Nazaré2
1Laboratório de Farmacologia Molecular, Instituto de Ciências Biológicas, Universidade Federal Do Pará, Belém, PA, Brazil. marcusoliveira@ufpa.br.
Molecular neurobiology
|July 30, 2023
概括
运动可以增强大脑的结构和功能,提高认知能力和生活质量. 这种非药物治疗有助于预防神经疾病和与年龄相关的认知衰退.
科学领域:
- 神经科学是一个神经科学.
- 运动生理学 运动生理学
- 认知健康 认知健康
背景情况:
- 身体炼是治疗神经疾病和认知衰老的公认的非药物治疗方法.
- 运动在多个层面上影响中枢神经系统 (CNS),影响大脑生理和结构.
- 这些变化促进认知增强,改善整体生活质量.
研究的目的:
- 审查身体炼影响大脑结构和功能的机制.
- 阐明运动诱导的大脑变化如何有助于认知改善.
- 为治疗肥胖,衰老,神经退行性疾病和创伤性脑损伤等疾病的治疗策略提供指导.
主要方法:
- 对实验和人类研究研究的审查.
- 对神经生物学机制的分析,这些机制是运动对大脑的影响的基础.
- 检查大脑结构和功能变化与认知结果之间的联系.
主要成果:
- 运动调节神经热素释放,成人海马神经发生和神经炎症.
- 大脑血液流动和结构性大脑重组受到运动的积极影响.
- 通过运动促进的社交互动也产生有益的认知结果.
结论:
- 了解运动介导的大脑可塑性对于治疗干预至关重要.
- 运动提供了一种整体的方法来缓解认知衰退和改善生活质量.
- 针对性炼干预可以使肥胖,老龄化人口,神经退行性疾病和TBI幸存者受益.
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