埃诺沙巴林作为机械中枢的多重体中的抗凝剂:一个案例报告
1Department of Thoracic and Cardiovascular Surgery, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.
Journal of chest surgery
|July 31, 2023
概括
对于带有机械心脏门的孕妇患者,素 (低分子量肝素) 为华法林提供了一个安全的替代品,可以预防血栓栓塞,而在此案例研究中没有不良影响.
科学领域:
- 心脏病学 心脏病学
- 产科 产科 产科 产科 产科
- 药理学 药理学是指药理学的学科.
背景情况:
- 机械心脏门更换需要抗凝剂来预防血栓栓塞.
- 怀孕期间使用华法林会带来胚胎病和中枢神经系统疾病的风险.
- 孕妇需要更安全的抗凝药替代品,如肝素.
研究的目的:
- 评估Enoxaparin在使用机械心脏门的孕妇患者的安全性和有效性.
- 为了评估在多发性患者的抗凝管理与机械中枢置换.
主要方法:
- 一名机械关置换患者在两次怀孕期间接受了埃诺沙巴林 (1 mg/kg每12小时).
- 使用抗Xa因子测试 (目标0.3-0.7 IU/mL) 监测埃诺沙林剂量.
- 静脉注射肝素在分娩前进行,产后恢复了华法林.
主要成果:
- 在怀孕或分娩期间没有观察到血栓栓塞并发症.
- 没有报告与素或肝素治疗相关的不良事件.
- 在具有机械心脏门的多发症患者中成功管理抗凝药.
结论:
- 埃诺沙巴林似乎是一种安全有效的抗凝药选择,适用于带有机械心脏门的孕妇患者.
- 这一案例表明,低分子量肝素可以在怀孕和分娩期间安全地管理.
- 需要进一步的大规模研究来证实这些发现.
相关概念视频
Mitral Valve Prolapse III: Nursing Management
16
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
16
Mitral Valve Prolapse II: Assessment and Management
22
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
22
Mitral Stenosis III: Medical Management
13
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
13
Mitral Regurgitation III: Medical Management
18
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
18
Mitral Stenosis IV: Nursing Management
14
A comprehensive nursing assessment is essential for patients with valvular heart disease, which involves any dysfunction of the heart valves that could impact blood flow and overall heart function.Subjective Data Collection:Chief Complaint and Present Illness: Start with the patient's primary concerns, focusing on the onset, duration, and progression of cardiac symptoms such as dyspnea, fatigue, chest pain, and palpitations.Past Medical History: Collect detailed information on any previous...
14
Mitral Regurgitation IV: Nursing Management
47
Mitral regurgitation (MR) is a condition where the mitral valve does not close properly, leading to the backward flow of blood from the left ventricle into the left atrium during systole. This condition can arise from various causes, including rheumatic fever, infective endocarditis, or degenerative valve disease. Effective nursing management is crucial to optimizing patient outcomes and involves comprehensive assessment and targeted interventions.Comprehensive Patient AssessmentA detailed...
47


