散布和阴茎mopox与他的病理相关性:两个单独的病例报告
Stephen S Koh1, Sherry M Youssef2, Mohsen Baghchechi3
1Department of Pathology and Dermatopathology, Kaiser Permanente, Orange County, Pasadena, California, USA.
Journal of cutaneous pathology
|July 31, 2023
概括
2022年mopox疫情带来了独特的挑战,最近的病例中观察到非典型的皮肤病变. 组织病理学揭示了这些mopox病变的特征性病毒变化.
科学领域:
- 传染性疾病 传染性疾病
- 皮肤病学 皮肤病学
- 病理学 病理学 病理学
背景情况:
- 2022年至2023年的mopox疫情代表了全球健康问题,扩展到非洲中部和西非的特有地区之外.
- 蒙波克斯病毒 (MPXV) 感染通常是自我限制的,并通过密切接触传播.
- 最近的mopox病例表现为非典型的表现,通常从皮肤病变开始,缺乏前兆症状.
研究的目的:
- 描述非典型的mpox皮肤病变的临床病理学发现.
- 为了将组织病理特征与mpox.的分子确认相关联.
主要方法:
- 案例介绍:两名中年男性感染mopox.
- 通过核酸放大试验确认mopox.
- 皮肤活检从mopox病变的组织病理学检查.
主要成果:
- 两位患者都出现了无痛的皮肤病变.
- 组织病理学揭示了作为一个关键特征.
- 在病变组织中观察到明显的病毒细胞病理变化.
结论:
- 莫波克斯的非典型表现,特别是无痛的皮肤病变,正在发生.
- 组织病理学对于诊断mopox至关重要,显示和病毒细胞病变效应.
- 了解mopox病变的组织病理学有助于在爆发期间进行诊断和管理.
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