阻断性睡眠呼吸暂停综合征 (OSAS) 与高血压老年患者认知功能障碍之间的相关性
Wei Xia1, Yongle Jing1, Chao Yuan1
1Department of Cardiology, Tianjin First Central Hospital, 300192 Tianjin, China.
Journal of integrative neuroscience
|July 31, 2023
概括
阻塞性睡眠呼吸暂停综合征 (OSAS) 与老年高血压患者的认知功能障碍有关. 解决OSAS可能会降低这一群体认知能力下降的风险.
科学领域:
- 老年学是一门学科.
- 神经学 神经学
- 睡眠医学 睡眠医学
背景情况:
- 阻塞性睡眠呼吸暂停综合征 (OSAS) 显著影响患者的生活质量和健康.
- 老年高血压患者是认知能力下降的脆弱群体.
研究的目的:
- 调查老年高血压患者OSAS和认知功能障碍之间的相关性.
- 为了确定OSAS是否会在这个人口群体中加剧认知障碍.
主要方法:
- 106名老年高血压患者被分为OSAS (n=45) 和非OSAS (n=61) 组.
- 通过便携式多睡眠学诊断出OSAS.
- 用蒙特利尔认知评估 (MoCA) 评估认知功能.
主要成果:
- 在OSAS组表现出更高的男性性别,心房动,高BMI,静脉压,和同类蛋白的比率.
- 患有OSAS的患者在视觉空间/执行能力,记忆力,注意力和总MoCA得分方面的得分明显较低.
- 在OSAS和认知功能障碍之间发现了正相关性 (r=0.224,p<0.05).
结论:
- 在老年高血压患者中,OSAS与认知功能障碍正相关.
- OSAS可能会通过直接影响或相关的并发症增加认知功能障碍的风险.
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