用于治疗气管狭窄症的冷疗法:系统性审查
Asma Hosna1, Muhammad Haseeb Ul Rasool2, Nicole C Noff3
1Internal Medicine, Icahn School of Medicine at Mount Sinai, New York City, USA.
Cureus
|July 31, 2023
概括
低温疗法为治疗输管后气管狭窄症提供了一种安全有效的替代方案,特别是在不能接受手术的患者中. 本次审查表明,与其他方法相比,临床改善显著,副作用较少.
科学领域:
- 肺部病理学 肺部病理学
- 关键护理医学 关键护理医学
- 干预性肺病学 干预性肺病学
背景情况:
- 气管狭窄 (TS) 是机械输管和气管切除术的日益严重的并发症,影响10-22%的患者.
- 严重的TS,其特点是无法对医疗管理做出反应的吸气性呼吸障碍,影响1-2%的受影响个体.
- 目前的激光手术和支架等治疗方法存在局限性,这凸显了对替代选择的需求,特别是对于不可手术的患者.
研究的目的:
- 审查冷疗法作为输管后气管管狭窄症治疗的疗效和安全性.
- 评估冷疗法的潜力,作为不可手术的气管狭窄症患者的替代方案.
主要方法:
- 进行了使用关键词"气道狭窄"或"气道阻塞"和"输管后"或"输出管后"或"气管切除术"和"冷疗法"的研究的系统审查.
- 这项分析包括了五项涉及67名患者的研究.
- 患者单独接受冷疗法或随后进行气球扩张.
主要成果:
- 总的来说,在67名患者中,48名患者在冷治疗干预后经历了临床改善.
- 大多数患者 (67人中65人) 没有出现并发症或仅出现轻微并发症.
- 与现有治疗方式相比,冷疗法显示出有利的安全性概况.
结论:
- 低温疗法为不可手术的气管狭窄症提供了可行的和有效的替代治疗方法.
- 该程序与显著的临床改善和较低的不良事件率有关.
- 对气管狭窄症的标准化冷治疗方案进行进一步的研究是有必要的.
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