惠普尔病的病例报告:一个具有挑战性的诊断
Filipa Nunes1, Martim Trovão Bastos1, Maria João Fernandes1
1Internal Medicine Department, Hospital Prof. Doutor Fernando da Fonseca, Lisbon, PRT.
威普勒是指一个鞭子.
科学领域:
- 传染性疾病 传染性疾病
- 胃肠病学 胃肠病学
- 肺部病理学 肺部病理学
背景情况:
- 惠普尔病是一种罕见的细菌感染,由Tropheryma whipplei引起.
- 它通常会影响关节和胃肠道,出现关节痛,腹痛,腹和体重减轻.
研究的目的:
- 报告一个非同寻常的惠普尔病病例,呈现出宪法综合征和显著的双侧膜溢出.
- 详细介绍用于识别这种非典型呈现中的*Tropheryma whipplei*的诊断方法.
- 描述成功的治疗方案和患者的结果.
主要方法:
- 一个48岁男性的案例研究,他患有无法解释的宪法症状和双侧多叶流液.
- 诊断程序包括小肠活检,揭示了巨细胞质 (PAS阳性) 中的杆状细菌.
- 使用聚合酶链反应 (PCR) 确认存在 *Tropheryma whipplei* DNA.
主要成果:
- 患者表现出宪法综合征和勃的双侧外流,这是惠普尔病的非典型表现.
- 对小肠活检的显微镜检查证实了Tropheryma whipplei的存在.
- 患者对静脉注射塞夫特里亚克松治疗疗程以及口服三甲胺/硫甲醇的治疗疗程反应良好,并实现了完全症状的消失.
结论:
- 惠普尔病可以表现为罕见和严重的表现,如显著的肺部溢液,超出其经典症状.
- 使用活检,PAS染色和PCR及时诊断对于识别*Tropheryma whipplei*至关重要.
- 长期服用抗生素,包括三甲prim/sulfamethoxazole,是有效的治疗惠普尔病,并实现一个有利的预后.
更多相关视频
07:50A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
03:34Laparoscopic Duodenum-Preserving Pancreatic Head Resection via Inferior Infracolic Approach: A Surgical Approach for Benign Lesions
Published on: February 9, 2024
相关概念视频
Chronic Pancreatitis II: Collaborative Care
Assessment:
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Nephrotic Syndrome II : Assessment and Medical Management
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
