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Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
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脏和副脊髓肌肉的表面扩散系数 (ADC) 测量的变量:一个单一中心的大队列研究
Yukun Chen1, Panpan Yang1, Caixia Fu2
1Department of Radiology, Changhai Hospital of Shanghai, Naval Medical University, Shanghai, 200433, China.
Heliyon
|July 31, 2023
概括
副脊髓肌肉是比脏更可靠的参考器官,可以在腹部扩散权重成像 (DWI) 中使明显扩散系数 (ADC) 的测量正常化. 这一发现提高了ADC肌肉和ADC脏评估的一致性.
科学领域:
- 放射学 放射学是一门学科.
- 医疗成像医学成像
- 扩散加权成像是一种扩散加权成像.
背景情况:
- 扩散加权成像 (DWI) 对于腹部成像至关重要.
- 表面扩散系数 (ADC) 测量需要正常化才能准确解释.
- 在ADC测量的变化可能会影响诊断可靠性.
研究的目的:
- 为了评估明显扩散系数 (ADC) 在脏 (ADC脏) 和副脊髓肌肉 (ADC肌肉) 中测量的变异性.
- 确定最佳的参考器官来规范腹部DWI的ADC值.
主要方法:
- 分析了来自1243名患者的腹部DWI数据,这些数据来自两个MRI扫描仪 (GE和西门子).
- 测量ADC脏和ADC肌肉,每次检查使用四个感兴趣的区域.
- 评估观察者间,扫描器间和扫描器内部 (可重复性) 的变化.
主要成果:
- 在两种扫描仪中,ADC肌肉显示出明显较低的可变性和比ADC脏更好的重复性和可比性.
- 布兰德-阿尔特曼分析显示,与ADC脏相比,ADC肌肉的协议极限较小.
- 对ADC肌肉的变化系数 (CV) 始终低于对ADC脏的变化系数 (p < 0.001).
结论:
- 副脊椎肌肉作为一个更稳定和可靠的参考器官,用于正常化腹部DWI ADC测量.
- 在临床实践中,利用副脊髓肌肉可以提高ADC肌肉和ADC脏评估的一致性和准确性.
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