周围插入的中央导管与癌症患者的植入式端口导管:一个元分析
Frontiers in oncology
|July 31, 2023
概括
植入的血管接入口 (PORT) 显示出更好的安全性比外围插入的中央导管 (PICCs) 用于化疗的管理,较少的不良事件. 建议在安全有效的化疗中使用PORT.
科学领域:
- 在瘤学瘤学.
- 医疗器械 医疗器械
- 临床试验 临床试验
背景情况:
- 化疗的使用需要可靠的血管通道.
- 植入的血管接入口 (PORT) 和外围插入的中央导管 (PICC) 是常见的策略.
- 与PICC相比,PORT的比较安全性和有效性仍在争论中.
研究的目的:
- 为了比较PORT和PICC在化疗中的临床和不良影响.
- 评估这两种血管接入方法的安全性和有效性.
主要方法:
- 一个系统的审查和对22篇文章的元分析.
- 在电子数据库中进行搜索:PubMed,Embase,Cochrane图书馆 (2023年5月).
- 包括对接受化疗的癌症患者中 PORT 和 PICC 的并发症率进行比较的研究. 使用Revman 5.3软件进行分析.
主要成果:
- 与PICC相比,PORT显示出一个优越的安全概况.
- 与PORTs.一起观察到的总体不良反应 (OR=2.72),导管相关血栓 (OR=2.84) 和过敏反应 (OR=6.26) 的发生率较低.
- 在深静脉血栓症 (DVT) (OR=2.00) 和感染 (OR=1.55) 方面注意到PICC非劣势.
结论:
- 与PICC相比,PORT在化疗中提供了显著的安全优势.
- PORT被认为是化学疗法的安全有效的血管接入选择.
- 需要进一步进行高质量的研究来确认临床益处,同时考虑经济因素.
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