评估和比较益生菌和合 bismuth 亚酸盐对腹部胀气的治疗作用
Maryam Soheilipour1, Elham Tabesh1, Soheila Najmi2
1Isfahan Gastroenterology and Hepatology Research Center (IGHRC), Isfahan University of Medical Sciences, Isfahan, Iran.
Caspian journal of internal medicine
|July 31, 2023
概括
益生菌显著降低功能性腹部胀气和腹的频率和严重程度. 体斯木亚酸盐也显示出显著的效果,改善患者的胀气症状.
科学领域:
- 胃肠病学 胃肠病学
- 微生物学 微生物学
- 临床医学 临床医学
背景情况:
- 功能性腹部膨胀是一种常见的功能性胃肠道疾病 (FGID).
- 研究FGID的有效治疗方法对于改善患者的生活质量至关重要.
研究的目的:
- 为了比较益生菌与合 bismuth 亚酸盐在管理功能性腹胀的疗效.
- 评估这些干预措施对相关胃肠道症状的影响.
主要方法:
- 这是一项双盲随机临床试验,涉及125名功能性腹部膨胀患者.
- 患者接受了familact益生菌药片,合 bismuth 亚酸盐片或安慰剂4周.
- 收集的数据包括膨胀的频率,严重程度,早期腹感,腹,吐和排便的频率.
主要成果:
- 益生菌组在2周后显示出明显较低的膨胀频率 (P=0.006).
- 与安慰剂 (P=0.001,P=0.037) 相比,在4周和8周内,益生菌和芝麻两组都显示出胀气频率降低 (P=0.001,P=0.037).
- 与其他组相比,益生菌的使用导致胀气严重程度显著降低,并且减少了的频率 (p<0.05).
结论:
- 益生菌的消费有效地改善了功能性腹部胀气的频率和严重程度.
- 益生菌还显示出在减少borborygmus方面具有显著的益处.
- 体斯木亚酸盐对膨胀症状产生显著的积极影响.
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